From 28 November to 5 December 2022, MVPE-CC Ghana received visit from the World Health Organisation (WHO) and the London School of Hygiene and Tropical Medicine (LSHTM). The purpose of the visit was to monitor study activities and follow-up on data management issues.

MVPE-CC is a multi-country study ongoing in Ghana, Kenya, and Malawi. The study is designed to determine the incremental benefit of the recommended 4 doses of the RTS,S vaccine over 3 doses when implemented through the routine childhood vaccine programme and to determine the association of the RTS,S vaccine with the safety signals identified in the Phase 3 trial of RTS,S. In addition, the study seeks to build the capacity of Expanded Programme on Immunisation (EPI) and National Malaria Elimination Programme (NMEP) managers on the use of case-control methodologies to monitor the effectiveness of RTS,S malaria vaccine and other vaccines.

As part of the trip to Ghana, the team made field visits to MVPE-CC clusters in the Bono and Central regions to observe field data collection and give feedback.

Team members: Dr Rafiq Okine (WHO), Prof Paul Milligan (LSHTM), Dr Paul Snell (LSHTM), Ari Fogelson (LSHTM)